Furthermore, the inhibitory molecules of NRF2, KEAP1, showed reduced levels (Fig
2019;29(2):320-334.e5
With increasing age, the number of ephelides and color intensity tend to diminish
Li C, Ou R, Wei Q, Shang H
Anti-Actin (AA128, Beyotime), anti-GPR109a (ab81825, Abcam, USA), anti-GPR43 (DF2746, Affinity Biosciences, USA), anti-H3 (anti-total histone H3, 4499, Cell Signaling Technology, CST, USA), anti-Ace-H3 (anti-pan-acetyl histone H3, 61637, Active Motif, USA), anti-p-AMPK (2535, adenosine monophosphate activated protein kinase, CST, USA), anti-p-ACC (11818, p-acetyl-CoA carboxylase, CST), anti-IR (anti-insulin receptor, ab5500, Abcam), anti-IRS-1 (anti-insulin receptor substrate-1, ab46800, Abcam), and anti-GLP-1R (NBP1-97308, Novus Biologicals, USA) were used in our study
All mechanistic and pharmacological findings are derived from short-duration preclinical models only