The nausea is generally most pronounced during the first few days after injection and often diminishes with subsequent doses
Among the remaining subjects, we further excluded those who received a diagnosis of bipolar disorder during the follow-up assessment (n = 9), those with missing metabolite data due to the lack of blood samples (n = 158) and those who did not complete the Inventory for Depressive Symptoms questionnaire (n = 33)
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Blood was collected from the saphenous vein, and blood glucose levels were measured using an ACCU-CHEK Guide Glucose Monitor and Testers (Roche) before each injection and at 10, 20, 30, 60, and 90 min after the glucose injection
Choose complex carbohydrates, such as whole grain breads and cereals, brown rice, oatmeal, quinoa, legumes and starchy vegetables like sweet potatoes and squash
Available evidence suggests no absolute contraindication, yet individual tolerability varies based on bile acid metabolism efficiency, pancreatic reserve, and underlying digestive symptoms prior to GLP-1 initiation