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MT2 also crosses the blood-brain barrier, producing centrally mediated effects (appetite suppression, libido modulation) that MT1 does not

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Recent Findings SGLT2-i consistently lower office SBP/DBP (2.54.0/1.52.0 mmHg) and 24-hour ambulatory BP (3.8/1.8 mmHg)

By 2050, this number is projected to more than double to 48.3 million

Those uses are research-context or off-label extrapolations from the peptides mechanism, not conclusions from adequate adult efficacy trials