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Liao, L
The signs and symptoms of this deficiency may include anemia, the buildup of too much acid in the body (metabolic acidosis), frequent infections, and symptoms caused by problems in the brain including seizures, intellectual disability, and loss of coordination (ataxia)
Cross-trial comparisons with dual-agonist agents such as tirzepatide are exploratory only no head-to-head trials have been conducted and should be interpreted with caution
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J Biol Chem 250:14221426 Huang CS, Moore WR, Meister A (1988) On the active site thiol of gamma-glutamylcysteine synthetase: relationships to catalysis, inhibition, and regulation
10.1172/jci95147 J
