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When these nutrients are deficient or the metabolic pathways become less efficient, homocysteine accumulates in the bloodstream and serves as a useful marker of impaired methylation and disrupted one carbon metabolism

The implication for clinical practice is that restoring youthful MOTS-c signaling might be a mechanistically legitimate target for longevity intervention

It is commonly found in meat and dairy products

The phosphorylation status of P53 was also assessed in whole-cell lysates

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Vollmers, C