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Phentermine, or combinations like phentermine-topiramate (Qsymia), are generally prescribed for short-term weight loss
Although many preclinical studies suggest that GLP-1R agonism can act directly on neurons to prevent cell death, this neuroprotective property may be secondary to reduced glucotoxicity and inflammation in the brain that can result from weight loss and improvements in glycemic control (Berkseth et al., 2014)
Prebiotic-rich foods (like onions, garlic, oats, asparagus) and possibly targeted probitoics may be worth exploring when improving metabolic health
Until then, PAs for weight-loss indications are ending and expire Dec 31, 2025
DiStefano, PhD, at cuanschutz.edu
Heavy textures and strong smells are hard for me right now
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