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The compounds work differently enough that direct dose translation is not valid
Genetic knockout mouse model lacking the itaconate-producing enzyme (Irg1/), along with treatment using the cell-permeable derivative octyl-itaconate ablation of mitochondrial itaconate production unleashed unbridled nuclear TET activity and exacerbated inflammation (119)
Wang Y, Qian H
No regulatory agency, and no peer-reviewed publication, has explained why
Who Should Approach Glutafine with Caution
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