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The insulin sensitivity advantage for tirzepatide is larger than weight loss alone explains (Diabetes, Obesity and Metabolism, 2025), which suggests the GIP component does real metabolic work beyond appetite suppression

Waist circumference will be measured with 250-cm-long non-elastic measurement tape

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Protocols generally do not double doses after a miss

Brain Behav Immun (2015) 50:196202.10.1016/j.bbi.2015.07.014 59 NiranjanR