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1 The British Society for Haematology does not recommend retesting vitamin B 12 levels after treatment has been initiated, and no guidelines address the optimal interval for screening high-risk patients

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In research settings semaglutide is studied for its activity at the GLP-1 receptor in cell-based metabolic and incretin-pathway models

[1] [2] However, longstanding neurological complications, such as peripheral neuropathy or cognitive changes, may require three to six months of consistent treatment before significant improvement occurs, and some damage may be irreversible if treatment is delayed