doi: 10.1001/jamacardio.2020.4511 68 VaduganathanMDochertyKFClaggettBLJhundPSde BoerRAHernandezAFet al
The mechanism of action involves several physiological effects: GLP-1 receptor agonists stimulate insulin secretion in a glucose-dependent manner, suppress glucagon release, slow gastric emptying, and reduce appetite through central nervous system pathways
TZDs improve peripheral insulin sensitivity
ABCC8 gene: The KCNJ11 gene (above) encodes one subunit of the ATP-sensitive potassium channel
Glutathione is naturally produced in the liver and is considered one of the bodys most important antioxidants, responsible for neutralising free radicals, supporting detoxification, and reducing oxidative stress
For those most sensitive, a blood sugar-regulating supplement may be indicated