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This distinguishes it from dual agonists such as tirzepatide and single agonists such as semaglutide, though no head-to-head comparative trials have been conducted and no superiority claims can be made at this stage

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In addition, the trial was conducted according to regulatory standards and comprised four renal impairment groups (including a group with ESRD) with more than ten subjects in each group and included a reference group with normal renal function that was comparable with respect to baseline characteristics [18, 19]

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