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The constant exposure of the renal system to toxins can cause nephrotoxicity (toxicity in the kidneys) which affects renal function

Physicians tend to administer a relatively low dose to start with, and gradually increase its strength

Furthermore, liraglutide has been shown to inhibit endoplasmic reticulum stress, as well as related apoptosis and inflammatory reactions are mediated through the cAMP/PKA/CREB pathway in BV2 cells that have been exposed to lipopolysaccharide (LPS) or tunicamycin (TM), a mouse-derived microglial cell line [111]

Importantly, five cases of T-DXdrelated interstitial lung disease (ILD) were reported in the phase I basket trial [32]

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Gastrointestinal events occurred most frequently during the dose escalation period and typically improved with continued treatment