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10.1038/s41569-018-0030-z Summary Keywords D-Gal, endothelial cell senescence, FOXO4-DRI, P53, ROS Citation Hu Z, Li F, Hu C, Shan Q, Tang Z, Jiang M, Yi X, Chen X, Jin L, Wang X and Wang Y (2026) FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway
In a 26-week rat oral toxicity study, AOD-9604 produced dose-dependent changes in serum osteocalcin (a bone-turnover marker) at week 13, with the direction reversing by week 26
Patients with chronic kidney disease, dialysis needs, or advanced liver conditions should only consider IV infusion under close medical supervision
Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency
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Each KO cell lines were generated by the CRISPRCas9 system with two different gRNAs shown in Supplementary table
