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They improve energy production, heart health, red blood cell formation, digestive health, brain functions, etc
Mechanistic preclinical studies suggest weight loss is mediated through GLP-1 receptors (GLP-1Rs) in the brain
Side effect profiles are similar between brand and compounded: gastrointestinal effects (nausea, constipation, diarrhea) during dose escalation
CRG/2022/000471)
Clinical trials have shown that Wegovy can lead to an average weight loss of about 15% of body weight over 68 weeks when combined with a healthy diet and regular exercise
The SELECT trial results established GLP-1 receptor activation as cardioprotective in ways that previous surrogate marker improvements only suggested
