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PMC 11031624
Beyond the biological evidence, existing systematic reviews suggest the potential hepatic benefits of SGLT2i therapy for T2D patients [36,37,38]
Within the GLP-1 receptor agonist class , other options available in the UK include: Dulaglutide (Trulicity) weekly injection with proven cardiovascular benefits [12] [17] Liraglutide (Victoza) daily injection with proven cardiovascular benefits [13] Exenatide (Byetta) twice-daily injection Exenatide extended-release (Bydureon) weekly injection Lixisenatide (Lyxumia) daily injection Tirzepatide (Mounjaro) weekly injection that acts on both GLP-1 and GIP receptors [14] [15] Whilst these medications share similar mechanisms to semaglutide, individual tolerability varies
Average duration of GLP-1 based therapies was 20.5 weeks
SIBO has been associated with dysfunctional intestinal motility, characterized by inadequate peristaltic action of gastrointestinal smooth muscle (171174), hypochlorhydria, and pancreatic exocrine insufficiency (175)
Gastroenterology and hepatology from bed to bench, 15(4), 326342
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