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It also reduces the intramitochondrial ratio of acetyl-CoA to free CoA, which in turn stimulates pyruvate dehydrogenase activity and promotes pyruvate oxidation

Based on similar clinical presentations and the lack of objective tests that demonstrate causality, it is hypothesized that chronic cannabis use can unmask symptoms in genetically predisposed individuals and cause hyperemesis.14 In addition, THC concentration in cannabis products has increased exponentially over time, which could also explain the paradoxical effects of cannabis use being an antiemetic at low doses and proemetic in high concentrations.53 Clinical subtypes of cyclic vomiting syndrome Recognizing the different CVS subtypes is possible through a detailed clinical history

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Immobility in this test was defined as the absence of any limb or body movements, except those caused by respiration

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