In our future work, we will examine the comparative effectiveness of alternative treatment options for obesity in patients who discontinue semaglutide or tirzepatide, to help patients and their clinicians make informed decisions. Cleveland Clinic is a nonprofit multispecialty academic medical center that integrates clinical and hospital care with research and education
Meanwhile, 51% of the GLP-1 drug users in the same survey say they plan to go on and off the medication based upon my needs. There are also concerns about the long-term effects of these drugs, adds Ackerman at Comet
From Endocrinology to Obesity Medicine: A Shift in Prescribing Authority The expansion of GLP-1 therapies into weight management has not only changed what these drugs are used for, but also who is prescribing them and under what clinical framework
Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology [published correction appears in Neurology
Moreover, whole exome sequencing (WES) was performed on symptomatic and asymptomatic family members (three duos), and selected variants were validated in a larger cohort to assess their potential role in disease severity [2]
Phase 2 data showed clinically significant weight loss across all dose arms above 4mg