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Description

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Although clinical studies have not demonstrated overt systemic depletion of NAD(P) during GLP-1RA therapy, sustained reductions in nutrient inflow may influence precursor availability and turnover kinetics, particularly in metabolically stressed populations

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Figure 5B), suggesting SEMA as a promising therapeutic intervention to partially revert dysmetabolic dependent pCAF alterations

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It works by mimicking a hormone called glucagon-like peptide-1 (GLP-1)

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