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( Figures 1 & 2 ) Imagine you already have a deficiency in your urea cycle activity but you have just enough activity to keep things going, then valproic acid is introduced and diminishes the ability to clear ammonia through that cycle even more

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We need to address the root cause: the way food is made, marketed, and consumed

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Twenty-one out of the 22 patients, all of whom had markedly elevated levels of pyroglutamic acid documented in urine and/or plasma, had taken APAP (only one was acute exposure to APAP)