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In general, however, urodynamics are not recommended for routine clinical use to establish an IC/BPS diagnosis

The gap is narrowing as newer GLP-1 and multi-receptor agonist medications are developed

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Sanjoy Dutta, chief scientific officer at Breakthrough T1D If people living with type 1 diabetes can avoid kidney failure or a heart attack, why should we deprive them of these medications? Prescribing off-label medications is legal, and even common in some cases

160 mg/day for children 7-10 years

NEJM 2023, PMID 37356779, ran 338 adults with obesity (mean BMI 37.3) but without type-2 diabetes for 48 weeks against placebo