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Potential Side Effects Common side effects of GLP-1 agonists, particularly during the initial weeks of weight loss treatment, include: Nausea Vomiting Diarrhea Headache Constipation Decreased appetite Pain in the right or middle upper stomach area Fatigue Dizziness Indigestion Injection site reactions (e.g., injection site rash, erythema) Conclusion GLP-1 agonists represent a promising pharmacological approach to weight management, offering significant benefits for individuals struggling with obesity or being overweight

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Patients starting from higher BMI (35+) may see faster initial results, but the rate stabilizes to 12 pounds weekly by month three as metabolic adaptation occurs

Presented for research literature review only Becerril S et al

Since distribution of GLP-1R in the kidney remains controversial, the renoprotective effects of GLP-1RAs may be partially explained by this mechanism

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