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Mechanism: Why these drugs work (and why they cause problems) Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) were initially approved in 2005 for the treatment of type 2 diabetes
This phenomenon is referred to as the oxidative burst or respiratory burst
The second is superoxide dismutase, SOD
Desensitization was shown to occur at around 40 days or roughly 4 weeks
Weight Loss: Over 6 months, patients on exenatide lost on average ~45 kg (811 lbs), whereas those on comparator therapies often lost little or even gained weight ( [6] ) ( [61] )
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