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Finally, dihydrolipoamide dehydrogenase activity in the glycine cleavage system (L protein) and in the -ketoacid dehydrogenase complexes (protein E3) catalyzes the conversion of the dihydrolipoyl moiety (reduced form) to the lipoyl moiety (oxidized form)

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Vitamin B12 deficiency is generally treated with intramuscular injections of vitamin B12, but people can also be treated with high oral doses