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The GLP-1 component of Retatrutide provides the established benefits of incretin therapy, while the addition of GIP receptor activation enhances insulin secretion and glucose uptake in peripheral tissues

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Hormones, particularly estrogen, also play a significant role by influencing fat storage and the elasticity of connective tissues

Compounded semaglutide is a custom-formulated version of the active ingredient found in medications like Ozempic and Wegovy