Uncommon but worth monitoring
Ketones in pregnancy: why is it considered necessary to avoid them and what is the evidence behind their perceived risk

Breaking down the numbers further: 5% weight loss achieved : 95% with tirzepatide vs 79% with semaglutide 10% weight loss achieved : 89% with tirzepatide vs 61% with semaglutide 15% weight loss achieved : 77% with tirzepatide vs 39% with semaglutide 20% weight loss achieved : 62% with tirzepatide vs 23% with semaglutide Diabetes Management For patients with type 2 diabetes, both medications offer significant benefits, though tirzepatide shows a slight edge: HbA1c reduction : Tirzepatide typically lowers HbA1c by 2-2.5%, while semaglutide achieves 1-2% reduction Fasting glucose improvement : Both medications effectively lower fasting blood sugar Time in range : Patients on both medications spend more time with blood sugars in the target range Insulin sensitivity : Tirzepatide may provide greater improvements in insulin sensitivity Cardiovascular Benefits Semaglutide has established cardiovascular benefits with FDA approval for reducing heart attack, stroke, and cardiovascular death risk in patients with type 2 diabetes or obesity with established heart disease

Tirzepatide represents the closest approved comparator to Retatrutide, differing only in the glucagon receptor component
(I wrote this article on genes linked to Hashimotos if you would like to learn more.) Because there is such a strong genetic component in the development of Hashimotos, this autoimmune condition is often thought to be hereditary
164 In another placebo-controlled trial that included 75 chronically stressed men, taking a 1% phospholipid-rich milk beverage daily for 42 days blunted the negative impact of stress on cognitive function