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Tirzepatide (Mounjaro, Zepbound) is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management and chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity
(2012) "Cigarette Smoking Increases Abdominal and Visceral Obesity but Not Overall Fatness: An Observational Study" PLOS One, 7(9) This article was reviewed and approved by Alice Fletcher, Lead Bariatric Dietician, and Lujain Alhassan, Bariatric Nutritionist, on 20 May 2025
Special Aspects Heart Failure in Diabetes and Chronic Kidney Disease (CKD) In patients with type 2 diabetes mellitus (T2DM), CKD and HF represent the two most common first presentations of cardiovascular or renal disease
N-acetylcysteine reduces contrast-associated nephropathy but not clinical events during long-term follow-up
What Clinical Evidence Says About GLP-1s and Cellulite Direct clinical trials of semaglutide have not specifically measured cellulite reduction as a primary outcome
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