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Fitbit Data Showed Activity Declines To investigate how activity levels changed after starting treatment, researchers analyzed data from the National Institutes of Health's All of Us Research Program, which combines electronic health records with Fitbit activity data

Patients often see weight loss beginning within the first few weeks, with the most substantial loss typically occurring within six months to a year of consistent use, depending on the individuals adherence to diet and exercise alongside the medication

The underlying mechanisms likely reflect complex interactions among genetic, metabolic, and environmental factors