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Clear dose-response relationship observed from 0.3 mg to 4.5 mg

Six years ago she reached 17st which, at 5ft 5in, meant she was severely obese and underwent gastric band surgery

Neal B, Perkovic V, Mahaffey KW, de Zeeuw D, Fulcher G, Erondu N, Shaw W, Law G, Desai M, Matthews DR, CANVAS Program Collaborative Group

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This, in turn, has a direct impact on the membrane's ability to function effectively in processes, such as signal transduction, the transport of molecules in and out of the cell, and the regulation of enzymes bound to the membrane [84]

Kristen Kistler MS, RD, LDN, outpatient dietitian at Ochsner LSU Health