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Our bodies are built to make and release GLP-1 on their own, so the real question is what changed to leave so many of us overweight despite that built-in system
Qin, 2012
In large clinical trials, participants with overweight or obesity who took tirzepatide lost, on average, 15% to 22% of their body weight over approximately 72 weeksa result that surpasses many other current weight loss medications
People who push for the highest dose fastest take on a disproportionate share of the risk
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Thus, increased insulin resistance may decrease the serotonergic neurons responsiveness to estradiol
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