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Phase 3 TRIUMPH-4 (NCT05931367) reported 28.7% body weight loss at 12 mg, 26.4% at 9 mg, vs 2.1% placebo at 68 weeks

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If you are not a candidate, your provider will tell you directly and walk you through the best next step

The preferential fat loss likely results from glucagon receptor activation, which increases resting energy expenditure and promotes fat oxidation as the primary fuel source, sparing protein catabolism for energy needs

Benefits Beyond Weight Loss In addition to significant weight reduction, semaglutide offers other health benefits, such as: Improved blood sugar control, which is particularly valuable for individuals with prediabetes or type 2 diabetes