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When you sweat, you lose sodium, which can affect hydration and performance, especially during exercise or in hot climates

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High temperatures increase mitochondrial membrane permeability and promote the release of cytochrome C, which in turn activates caspase-9 and the downstream caspase-3/7 cascade (Zou et al., 1999

Each dose tier delivered roughly 3 additional percentage points of weight loss, representing a linear dose-response relationship that holds across the full tested range

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