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The GC gene is located on chromosome 4q13.3 and is composed of 15 exons that generate three alternatively spliced mRNAs that encoded two different protein isoforms

31 Although it is unclear how or why pain sensitization develops, researchers have identified several possible theories, some of which are detailed below

With the help of the enzyme glutathione reductase, it can be recycled and turned back into active glutathione or GSH

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