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While 2.5 mg may produce initial appetite suppression and modest weight loss, clinical data shows this dose provides suboptimal long term efficacy
It belongs to a class of medicines called glucagon-like peptide-1 (GLP-1) receptor agonists , which work by mimicking the action of a naturally occurring hormone that regulates blood sugar levels
But 28 days is the conservative, widely accepted standard
Future trials are needed to confirm whether GLP-1 drugs might be effective in preventing Alzheimers disease. Declared interests: Prof Sir John Hardy: I have consulted for Eisai and Eli Lilly Prof Paresh Malhotra: I receive research funding from NIHR, MRC, Dementia Platforms UK, Alzheimers Research UK, the Football Association, British Heart Foundation and Alzheimers Society
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