More dopamine could mean more cravings
Three human studies have now been published (as of early 2026), all showing positive results with zero adverse events
Importantly, impaired hepatic metabolic function can compromise carnitine biosynthetic capacity, potentially leading to relative deficiency that may contribute to hepatic lipid accumulation, inflammatory activation, oxidative stress, and insulin resistance
Typically, swelling lasts around 714 days
Why Project Orbis Proves the FDA Can Build Alliances the EMA Cannot Project Orbis is the FDAs oncology concurrent-review initiative, operating with partners including Australias TGA, Canadas Health Canada, the UKs MHRA, Switzerlands Swissmedic, Brazils ANVISA, Singapores HSA, and Israels Ministry of Health
Additionally, many patients with type 2 diabetes take metformin, which can cause vitamin B12 deficiency with long-term use and potentially contribute to anemia