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In pernicious anemia, parenteral vitamin B12 is needed long term, and monthly injections may be required for life
This is because methylcobalamin B12 acts on the bone marrow to normalize red blood cell formation
no completed efficacy trials of injectable systemic GHK-Cu
Folate supplementation must not be started before B12 deficiency is treated, as this can precipitate or worsen neurological complications
High blood pressure and bone-mineral loss in elderly white women: a prospective study
Why Injections Beat Pills (For Most People) The simple math: injectable B12 bypasses the stomach acid, liver metabolism, and intestinal absorption issues that limit oral B12 to about 1% bioavailability in most adults
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