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Obesity 21 , 21632171 (2013)
Genetic and pharmacologic NNMT suppression reduces adiposity and improves metabolic readouts in preclinical models, with supportive cellular data showing increases in NAD and SAM and suppression of lipogenesis
Patients should be closely monitored for signs of adverse effects during therapy
International Journal of Molecular Medicine, 31 (1), 9198
Nat Cell Biol 16:11801191 Dixon SJ, Stockwell BR (2014) The role of iron and reactive oxygen species in cell death
May influence gene expression related to repair processes
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