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Time-based hydration rather than thirst-based becomes necessary

10.1016/j.placenta.2016.12.005 Placenta 71 GrayM

After 50, the body naturally loses muscle mass at a rate of 1-2% per year (sarcopenia), and adding semaglutide-driven calorie restriction on top of age-related muscle loss can be devastating

The most relevant metabolic effects expected from the GLP-1RA are summarized in Table 2