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Data are presented as meanSE ( N =5)

Retatrutides 24.2% average weight loss in Phase 2 trials represents the highest ever recorded in obesity pharmacotherapy

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Common side effects are gastrointestinal nausea, vomiting, and diarrhoea and are most pronounced during dose escalation

There have been anecdotal reports of some patients using these drugs for weight loss and then presenting with repeated episodes of nausea and vomiting secondary to a condition referred to as gastroparesis, said senior author Dr