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This causes the immune system to make substances that cause the symptoms of illness, like brain fog, appetite loss, and reduced interest in your favorite activities

Research has shown that between 50% and 98% of injected vitamin B12 is found in the urine 48 hours after it is administered

Injecting into a vein may mean some of the vitamin is wasted, as it can leave the body via the urine

Older adults A 2015 review suggests that adults over the age of 60 may be more likely to have a vitamin B12 deficiency

In terms of weight loss, if you have a vitamin B12 deficiency, which is likely, you will lose some of the vitamin B12 shot in the first 48 hours, but at least 50% of it will be stored in your liver

If the body properly uses B12, studies show it can stay in the body for up to five years