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In a 24-week study of 206 overweight patients who were randomized to continue on olanzapine, quetiapine, or risperidone or to switch to aripiprazole, patients who switched to aripiprazole experienced significantly greater weight reduction (3.7 kg) compared to patients who continued on their previous medications (0.7 kg) (Stroup TS et al, Am J Psychiatry 2011;168(9):947956)
Relying on the medication alone without addressing movement, muscle preservation, and nutrition could mean trading one health risk for another
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Monthly costs range from $117 to $359 depending on the medication and plan, with insurance accepted to help offset costs
Thus, the plasma homocysteine level would be stronger than that of the frequency of this genetic defect to predict the incidence of atherothrombotic disease
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