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While the medication can cause constipation in some people, it may also help reduce hemorrhoid risk through weight loss
Patients who eat adequate protein and calories while on tirzepatide rarely report significant tiredness
Like most research peptides, retatrutide is sensitive to heat, light, repeated freeze-thaw cycles, and prolonged exposure at ambient temperatures
For individuals who require significant weight reduction, medically supervised options such as very-low-calorie diets (VLCDs), GLP-1 medications, or bariatric procedures may be considered depending on overall health status
New England Journal of Medicine, 382(6), 2034-2046
Rosen , Julie R
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