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Br J Dermatol

2.2 Targeting PDE1B and PDE10A isoforms in the therapeutic aspect of schizophrenia PDEs, particularly PDE1B and PDE10A, are predominantly expressed in the striatum, a locus critically involved in dopaminergic neurotransmission

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References Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA