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Illuminating NAD(+) metabolism in live cells and in vivo using a genetically encoded fluorescent sensor

[10] Scientists conclude that that the short time course of resensitisation following acute octreotide withdrawal is suggestive of an effect(s) on receptor function or on the receptor signal transduction cascade at sites further downstream, rather than an immune-mediated phenomenon. Studies have suggested peptide-induced production of GHRH receptors, rather than a down-regulation of them

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These applications remain speculative pending human research, but the biological plausibility is strong