Each subunit is characterized by the GST-typical modular structure with two spatially distinct domains
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Cobalamin C defect causes impaired conversion of dietary vitamin B12 into its two metabolically active forms, methylcobalamin and adenosylcobalamin (164)
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Moreover, inflammatory factors induced by high salt intake can shift the tumor microenvironment towards a pro-inflammatory state, which may inhibit tumor progression
Understanding why these reactions happen, how to manage symptoms effectively, and when medical evaluation is necessary helps patients safely continue treatment while minimizing discomfort and maintaining optimal medication adherence