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Hepatology 34 , 11581163 (2001)

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As IKK- is the direct upstream kinase that phosphorylates IB-, leading to its degradation, we next examined whether decreased TNF-induced IB- phosphorylation by H 2 O 2 treatment was due to its effects on IKK- activity

These findings set the stage for the mechanistic exploration in Sections 3 and 4, where we discuss how metabolic reprogramming and immune interactions converge to regulate ferroptosis in OA

Its a synthetic version of folate, one of the B vitamins