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GLP-1 (Glucagon-like Peptide-1) receptor agonists, such as Semaglutide GLP-1 and Liraglutide (Victoza), are increasingly becoming an integral part of our treatment strategies

This dual-pathway approach: Enhances weight loss beyond either agent alone May reduce GI side effects by lowering required GLP-1 doses Improves long-term metabolic reprogramming What the Research Says Clinical Trials on Cagrilintide: Amylin Pharma developed and tested Cagrilintide in Phase 2 trials

Furthermore, recent investigations reported that empaglifozin is able to restore ion hemostasis in failing cardiac myocytes, reducing intracellular sodium overload by the inhibition of the sarcolemmal Na+/H+ exchanger (Packer, 2019)

Pregnancy and breastfeeding : Both medications should be avoided during pregnancy and breastfeeding

It means the drug actively protects the heart beyond what weight loss alone would explain

Tirzepatide became the answer