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Since patients are generally more willing to accept that trade-off following massive weight loss versus, say, a 20-pound change, surgeons are engineering new lift techniques for people who have lost smaller amounts of weight rapidly on GLP-1s

Fred Sattler at University of Southern California Keck School of Medicine

"You know, that's not necessarily what goes on in clinical practice," she says

Peptide identity Gly-His-Lys, a three-residue peptide

For example, AstraZeneca recently spent $2 billion to license an experimental pill that might have fewer side effects than the injectable treatments