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Larazotide is a peptide designed specifically to address intestinal permeability, commonly known as leaky gut. This condition occurs when the tight junctions in the intestinal lining loosen, allowing toxins, pathogens, and undigested food particles to escape into the bloodstream

And then it, um, it's supposed to mimic the active region of this protein

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In the recessive inheritance model, there was a 64% protection against the development of DR (OR [95% CI] = 0.358 [0.960 1.205], p = 0.001), which remained significant after adjustment for sex, ethnicity, glycated hemoglobin, and arterial hypertension