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The in vitro metabolism of benzo(a)pyrene by microsomes prepared from control and benz(a)anthracene induced cultured keratinocytes was also inhibited by clotrimazole with greater inhibitory effect on benz(a)anthracene induced keratinocytes especially with respect to the formation of diols and quinones

WARNINGS: Do not exceed the recommended daily dose

Then, the OD 600 of these precultures was measured and fresh cultures were prepared in 120 ml of SDCAA medium in a 250-ml flask (OD 600 = 0.3)

Patch Test First: If you have sensitive skin, test the lotion on a small area before full application to ensure no adverse reactions

Bibcode:1993FEMME..12..143D