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Therefore, a GLP-1 sensitizer will have a beneficial effect in preventing NASH

No interaction studies have been conducted, and retatrutide remains an investigational compound without MHRA authorisation in the UK, meaning this combination is not supported by current evidence-based practice

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some of the study period preceded the approval of semaglutide and tirzepatide to treat obesity

Safety: Handle using appropriate personal protective equipment (PPE) such as gloves, lab coat, and eye protection, within a controlled laboratory environment

doi: 10.2174/0929866522666151013130742 56 de AzevedoR